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Results for "

antiplatelet activity

" in MedChemExpress (MCE) Product Catalog:

47

Inhibitors & Agonists

1

Biochemical Assay Reagents

2

Peptides

25

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N9488
    Girinimbine

    Girinimbin

    		 Apoptosis Bacterial Parasite Infection Inflammation/Immunology Cancer
    Girinimbine (Girinimbin) is a carbazole alkaloid with a variety of biological effects. Girinimbine can induce apoptosis, and has antitrypanosomal, antiplatelet activity, antibacterial activity, anti-inflammatory, antioxidant and antitumor activities .
    Girinimbine
  • HY-N0293
    Paeoniflorin
    Maximum Cited Publications
    16 Publications Verification

    Peoniflorin

    		 HSP Infection Neurological Disease Cancer
    Paeoniflorin is a heat shock protein-inducing compound and commonly exists in the plants of Paeoniaceae family, with various biological activities, including anticancer activity, anti-inflammatory activity, enhancing cognition and attenuating learning impairment, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, and reducing blood viscosity .
    Paeoniflorin
  • HY-146498
    Antiplatelet agent 1

    		P2Y Receptor Cardiovascular Disease Cancer
    Antiplatelet agent 1 (compound 7q) is a Ticagrelor analoguehas, possessing antiplatelet activity. Antiplatelet agent 1 can be used for researching platelet aggregation .
    Antiplatelet agent 1
  • HY-146499
    Antiplatelet agent 2

    		P2Y Receptor Cardiovascular Disease Cancer
    Antiplatelet agent 2 (compound 7p) is a Ticagrelor analoguehas, possessing antiplatelet activity. Antiplatelet agent 2 can be used for researching platelet aggregation .
    Antiplatelet agent 2
  • HY-N7991
    Rubiayannone A

    		Others Cardiovascular Disease
    Rubiayannone A is an anthraquinone glycoside with an antiplatelet aggregation activity .
    Rubiayannone A
  • HY-19163
    SC-52012

    		Others Cardiovascular Disease
    HY-19163 is an orally active fibrinogen receptor antagonist, with antiplatelet activities.
    SC-52012
  • HY-N3048
    Piperlotine D

    		Others Cardiovascular Disease
    Piperlotine D is an antiplatelet aggregation agent. Piperlotine D can be extracted from Piper lolot with antiplatelet aggregation activity. Piperlotine D inhibits arachidonic acid-induced platelet aggregation with an IC50 of 43.4 μg/mL .
    Piperlotine D
  • HY-33351
    Eugenin

    Eugenin is a chromone isolated from Peucedanum japonicum, with potent antiplatelet aggregation activity .
    Eugenin
  • HY-N3051
    Piperlotine A

    		Others Cardiovascular Disease
    Piperlotine A is an alkaloid isolated from Piper lolot, with potent antiplatelet aggregation activity .
    Piperlotine A
  • HY-N0320
    Salvianolic acid D

    		Others Cardiovascular Disease
    Salvianolic acid D, isolated from Salvia miltiorrhiza, is a potential antiplatelet activity compound .
    Salvianolic acid D
  • HY-101700
    LCB-2853

    		Prostaglandin Receptor Cardiovascular Disease
    LCB-2853 is an antagonist of thromboxane A2 (TXA2) receptor, with antiplatelet and antithrombotic activities.
    LCB-2853
  • HY-N1505
    Loureirin A
    5 Publications Verification

    		 Akt Cardiovascular Disease
    Loureirin A is a flavonoid extracted from Dragon's Blood, can inhibit Akt phosphorylation, and has antiplatelet activity.
    Loureirin A
  • HY-N2909
    Aurantiamide

    		Others Inflammation/Immunology
    Aurantiamide is an orally active constituent of Portulaca oleracea L and has various biological activities, including antioxidant, antiplatelet, anti-inflammatory, and antitumor activities .
    Aurantiamide
  • HY-N3668
    Cyclomorusin

    Cyclomorusin A; Cyclomulberrochromene

    		 Others Cardiovascular Disease
    Cyclomorusin (Cyclomorusin A; Cyclomulberrochromene) is a prenylflavonoid with antiplatelet activity. Cyclomorusin also inhibits markedly collagen-induced platelet aggregation .
    Cyclomorusin
  • HY-118072
    Aspalatone

    		Others Neurological Disease
    Aspalatone is an orally active antiplatelet aggregant with IC50 of 180 μM. Aspalatone has antioxidant and neuroprotective activities .
    Aspalatone
  • HY-B0686
    Eptifibatide
    5 Publications Verification

    		 Integrin Cardiovascular Disease
    Eptifibatide is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .
    Eptifibatide
  • HY-B0686A
    Eptifibatide monoacetate

    		Integrin Cardiovascular Disease
    Eptifibatide monoacetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .
    Eptifibatide monoacetate
  • HY-N2299
    Morusinol

    		Others Cardiovascular Disease
    Morusinol is a flavonoid isolated from Morus alba root bark. Morusinol has an antiplatelet activity and  significantly inhibits arterial thrombosis in vivo .
    Morusinol
  • HY-B0647A
    (3S)-Butylphthalide

    (-)-3-n-Butylphthalide; (3S)-Butylphthalide
    (3S)-Butylphthalide is a phthalide and can be isolated from A. graveolens. (3S)-Butylphthalide has antiplatelet and neuroprotective activities .
    (3S)-Butylphthalide
  • HY-N6020A
    (+)-Butin

    		Others Others
    (+)-Butin is the R enantiomer of Butin. Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities .
    (+)-Butin
  • HY-N6020
    (-)-Butin

    		Others Inflammation/Immunology
    (-)-Butin is the S enantiomer of Butin. Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities .
    (-)-Butin
  • HY-N4228
    6-Methoxydihydroavicine

    		Platelet-activating Factor Receptor (PAFR) Cancer
    6-Methoxydihydroavicine is an alkaloid isolated from Zanthoxylum integrifoliolum. 6-Methoxydihydroavicine has antiplatelet activities and inhibits AA-, collagen- and PAF-induced platelet aggregation in vitro .
    6-Methoxydihydroavicine
  • HY-N2081
    Skimmianine
    1 Publications Verification

    		 Others Inflammation/Immunology Cancer
    Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity .
    Skimmianine
  • HY-N6005
    Methyl caffeate

    		Bacterial Infection Cancer
    Methyl caffeate, an antimicrobial agent, shows moderate antimicrobial and prominent antimycobacterial activities. Methyl caffeate also exhibits α-glucosidase inhibition activity, oxidative stress inhibiting activity, anti-platelet activity, antiproliferative activity in cervix adenocarcinoma and anticancer activity in lung and leukmia cell lines .
    Methyl caffeate
  • HY-U00367
    (4E)-SUN9221

    		Adrenergic Receptor 5-HT Receptor Cardiovascular Disease Endocrinology
    (4E)-SUN9221 is a potent antagonist of α1-adrenergic receptor and 5-HT2 receptor, with antihypertensive and anti-platelet aggregation activities.
    (4E)-SUN9221
  • HY-B0366A
    Cyproheptadine hydrochloride
    3 Publications Verification

    		 5-HT Receptor Cardiovascular Disease Neurological Disease Cancer
    Cyproheptadine hydrochloride is a potent and orally active 5-HT2A receptor antagonist, with antidepressant and antiserotonergic effects. Cyproheptadine hydrochloride has antiplatelet and thromboprotective activities. Cyproheptadine hydrochloride can be used for the research of thromboembolic disorders .
    Cyproheptadine hydrochloride
  • HY-126562
    Piperlonguminine

    		Bacterial Fungal Antibiotic Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
    Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows various biological properties, including anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibacterial activities .
    Piperlonguminine
  • HY-B1622
    Cyproheptadine
    2 Publications Verification

    		 5-HT Receptor Apoptosis Cardiovascular Disease Neurological Disease
    Cyproheptadine is a potent and orally active 5-HT2A receptor antagonist, with antidepressant and antiserotonergic effects. Cyproheptadine has antiplatelet and thromboprotective activities. Cyproheptadine can be used for the research of thromboembolic disorders .
    Cyproheptadine
  • HY-110118
    Edaglitazone

    		PPAR
    Edaglitazone is a potent, selective and orally active PPARγ agonist, with EC50s of 35.6 nM and 1053 nM for PPARα and PPARγ, respectively. Edaglitazone displays antiplatelet, antidiabetic and anti-hyperglycemic activity .
    Edaglitazone
  • HY-111447
    VAS 3947

    		NADPH Oxidase Apoptosis Cardiovascular Disease Cancer
    VAS 3947, a specific NADPH oxidase (NOX) inhibitor, exerts a potent antiplatelet effect. VAS3947 induces apoptosis independently of anti-NOX activity, via UPR activation, mainly due to aggregation and misfolding of proteins .
    VAS 3947
  • HY-N11920
    Kadsurenin B

    		Platelet-activating Factor Receptor (PAFR) Infection Neurological Disease Inflammation/Immunology
    Kadsurenin B is a PAF (platelet-activating factor) antagonist with neuroprotective activity. Kadsurenin B has a wide range of pharmacological research potential, such as antibacterial, anti-inflammatory, neuroprotective, antioxidant, antiplatelet aggregation, cytotoxic, antiparasitic, etc .
    Kadsurenin B
  • HY-A0221
    Ridogrel

    R 68070

    		 Prostaglandin Receptor Inflammation/Immunology
    Ridogrel (R 68070) is an orally active combined thromboxane A2 synthetase inhibitor and thromboxane A2/prostaglandin endoperoxide receptor blocker. Ridogrel is potent antiplatelet agent. Anti-inflammatory activities .
    Ridogrel
  • HY-N8425
    Octacosanoic acid

    Montanic acid

    		 Endogenous Metabolite Metabolic Disease
    Octacosanoic acid is a very long-chain saturated fatty acid. It is the major component of D-003, a mixture of very long-chain aliphatic acids purified from sugar cane wax that has antiplatelet and cholesterol-lowering activities in animal models .
    Octacosanoic acid
  • HY-B1735
    Picotamide

    Picotamide is a combined inhibitor of thromboxane A2 (TxA2) synthase and receptor. Picotamide has antiplatelet activity. Picotamide promotes the reduction of microalbuminuria and the inhibition of growth of carotid plaques in diabetes. Picotamide can be used for researching acute or chronic cardiovascular diseases .
    Picotamide
  • HY-N12067
    Columbianetin β-D-glucopyranoside

    		Others Inflammation/Immunology
    Columbianetin β-D-glucopyranoside can be isolated from Angelicae pubescentis radix and has antiplatelet aggregation, anti-inflammatory and analgesic activities. Columbianetin β-D-glucopyranoside exerts significant protective effects against glutamate-induced toxicity .
    Columbianetin β-D-glucopyranoside
  • HY-N0607
    Ginsenoside Ro
    1 Publications Verification

    Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V

    		 Calcium Channel Prostaglandin Receptor Cardiovascular Disease Endocrinology
    Ginsenoside Ro (Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V) exhibits a Ca 2+-antagonistic antiplatelet effect with an IC50 of 155  μM. Ginsenoside Ro reduces the production of TXA2 more than it reduces the activities of COX-1 and TXAS.
    Ginsenoside Ro
  • HY-N6020B
    Butin

    		Others Cardiovascular Disease Inflammation/Immunology
    Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities. Butin significantly alleviates myocardial infarction and improves heart function, together with prevents diabetes-induced cardiac oxidative damage in rat .
    Butin
  • HY-N0120
    (E/Z)-Polydatin

    (E/Z)-Piceid

    		 Others Inflammation/Immunology
    (E/Z)-Polydatin ((E/Z)-Piceid) is a monocrystalline compound originally isolated from the root and rhizome of Polygonum cuspidatum. (E/Z)-Polydatin has anti-platelet aggregation, anti-oxidative action of low-density lipoprotein (LDL), cardioprotective activity, anti-inflammatory and immune-regulating functions .
    (E/Z)-Polydatin
  • HY-W062836
    BAY 41-8543

    		Guanylate Cyclase Cardiovascular Disease
    BAY 41-8543 is an orally active, nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC). BAY 41-8543 has vasodilator activity in the pulmonary and systemic vascular beds in the rat. BAY 41-8543 has antiplatelet effects and has the potential for cardiovascular diseases research .
    BAY 41-8543
  • HY-N3665
    Cyclocommunol

    		Tyrosinase Cancer
    Cyclocommunol is a prenylflavonoid with antityrosinase and antiplatelet activitie, can be solated from breadfruit. Cyclocommunol exerts anti-tumor activity and inhibits the growth of human hepatoma and gastric cancer cells with IC50 values between 16 and 80 µM. Cyclocommunol shows proapoptotic effect on oral squamous cell carcinoma (OSCC) .
    Cyclocommunol
  • HY-N1631
    1-Hydroxyrutecarpine

    1-Hydroxyrutaecarpine

    		 Others Others
    1-Hydroxyrutaecarpine (compound 1a) is a hydroxy-derivative of rutaecarpine. 1-Hydroxyrutaecarpine shows cytotoxicities with ED50s of 3.72, 7.44 µg/mL for P-388 and HT-29 cells, respectively. 1-Hydroxyrutaecarpine shows antiplatelet activity .
    1-Hydroxyrutecarpine
  • HY-105218
    Ifetroban

    BMS-180291

    		 Prostaglandin Receptor Cardiovascular Disease Endocrinology Cancer
    Ifetroban (BMS-180291) is an orally active antagonist of thromboxane A2 (TXA2) or prostaglandin H2 (PGH2) receptor. Ifetroban shows antiplatelet activity, and inhibits tumor cell migration without affecting cell proliferation. Ifetroban can be used for myocardial ischemia, hypertension, stroke, thrombosis, cardiomyopathy research .
    Ifetroban
  • HY-105218A
    Ifetroban sodium
    1 Publications Verification

    BMS-180291 sodium

    		 Prostaglandin Receptor Cardiovascular Disease Endocrinology Cancer
    Ifetroban (BMS-180291) sodium is an orally active antagonist of thromboxane A2 (TXA2) or prostaglandin H2 (PGH2) receptor. Ifetroban sodium shows antiplatelet activity, and inhibits tumor cell migration without affecting cell proliferation. Ifetroban sodium can be used for myocardial ischemia, hypertension, stroke, thrombosis, cardiomyopathy research .
    Ifetroban sodium
  • HY-N2435
    [8]-Shogaol

    		COX Apoptosis Cancer
    [8]-Shogaol, a kind of stimulating compound in ginger, has antiplatelet (IC50=5 μM), anti-cancer and anti-inflammatory activity. [8]-Shogaol inhibited COX-2 (IC50=17.5 μM), which led to the decline of human leukemia cells. 8-Shogaol Selective direction TAK1 sum TAK1-TAB1 (IC50=5 μM), suppress IKK, Akt sum MAPK signal pathway, and reverse synovitis synovial sum Air dampness (RA).
    [8]-Shogaol
  • HY-P1956
    Human serum albumin
    1 Publications Verification

    HSA

    		 NF-κB NO Synthase Cardiovascular Disease Inflammation/Immunology
    Human serum albumin (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, NF-κB, and peroxynitrite (ONOO −) in the vascular wall, contributing to the reduction of blood pressure .
    Human serum albumin
  • HY-N2515
    Ginsenoside Rk1
    2 Publications Verification

    		 NF-κB PI3K JAK Apoptosis Inflammation/Immunology Cancer
    Ginsenoside Rk1 is a unique component created by processing the ginseng plant (mainly Sung Ginseng, SG) at high temperatures . Ginsenoside Rk1 has anti-inflammatory effect, suppresses the activation of Jak2/Stat3 signaling pathway and NF-κB . Ginsenoside Rk1 has anti-tumor effect, antiplatelet aggregation activities, anti-insulin resistance, nephroprotective effect, antimicrobial effect, cognitive function enhancement, lipid accumulation reduction and prevents osteoporosis . Ginsenoside Rk1 induces cell apoptosis by triggering intracellular reactive oxygen species (ROS) generation and blocking PI3K/Akt pathway .
    Ginsenoside Rk1
  • HY-149454
    P2Y1/P2Y12 antagonist-1

    		P2Y Receptor Cancer
    P2Y1/P2Y12 antagonist-1 (compound 24w) is an orally available dual inhibitor of P2Y1 and P2Y12 with antiplatelet activity. P2Y1/P2Y12 antagonist-1 inhibits ADP-induced platelet aggregation in rabbit plasma with an IC50 of 4.23 μM. P2Y1/P2Y12 antagonist-1 exhibits potent inhibitory effects in rat thrombosis model.
    P2Y1/P2Y12 antagonist-1

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